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Search Results for " cathepsin v "

Targets Recommended: Cysteine Protease

2

抑制剂 & 化合物

1

天然产物

3

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T13288	VBY-825	Cysteine Protease	Proteases/Proteasome
	VBY-825是cathepsin 一种新型的可逆抑制剂，对cathepsin B, L, S 和V 都有很高的抑制力。
T40463	Relacatib SB-462795
	Relacatib (SB-462795) is a novel, potent, and orally active inhibitor of human cathepsins K, L, and V. It exhibits high affinity for these enzymes, with Ki values of 41 pM, 68 pM, and 53 pM, respectively. Moreover, Relacatib effectively inhibits endogenous cathepsin K in situ in human osteoclasts, as well as human osteoclast-mediated bone resorption, with IC 50 values of 45 nM and 70 nM, respectively. Additionally, in vitro studies demonstrate Relacatib's inhibitory effect on bone resorption in ...

化合物

Cat.No: T13288

Target: Cysteine Protease

Cat.No: T40463

Synonym: SB-462795

Cat. No.	Product Name	Target	Signaling Pathways
T19392	L-Homocysteine	Others	Others
	L-Homocysteine, an L-configured homocysteine metabolite, induces the upregulation of cathepsin V, which mediates vascular endothelial inflammation in hyperhomocysteinaemia.

天然产物

Cat.No: T19392

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01249	Cathepsin V Protein, Human, Recombinant (His) CTSV,cathepsin V,MGC125957,CATL2,...	Human	HEK293 Cells
	Cathepsin V (CTSV), also known as Cathepsin L2, CTSL2, and CATL2, is a member of the peptidase C1 family. It is predominantly expressed in the thymus and testis. Cathepsin V is also expressed in corneal epithelium, and to a lesser extent in conjuctival epithelium and skin. It is a lysosomal cysteine proteinase that may play an important role in corneal physiology. It has about 75% protein sequence identity to murine cathepsin L. The fold of this enzyme is similar to the fold adopted by other mem...
TMPH-00134	AcMNPV Viral cathepsin Protein (His & SUMO) Cysteine proteinase,Viral cathepsin,V<...	AcMNPV	E. coli
	Cysteine protease that plays an essential role in host liquefaction to facilitate horizontal transmission of the virus. Accumulates within infected cells as an inactive proenzyme (proV-CATH), which is activated by proteolytic cleavage upon cell death. AcMNPV Viral cathepsin Protein (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 39.9 kDa and the accession number is P25783.
TMPH-00060	ApNPV Viral cathepsin Protein (His & Myc) V-cath,Viral cathepsin,Cysteine p...	ApNPV	E. coli
	Cysteine protease that plays an essential role in host liquefaction to facilitate horizontal transmission of the virus. May participate in the degradation of foreign protein expressed by the baculovirus system. ApNPV Viral cathepsin Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 31.1 kDa and the accession number is Q91CL9.

重组蛋白

Cathepsin V Protein, Human, Recombinant (His)

Cat.No: TMPY-01249

Species: Human

Expression System: HEK293 Cells

AcMNPV Viral cathepsin Protein (His & SUMO)

Cat.No: TMPH-00134

Species: AcMNPV

Expression System: E. coli

ApNPV Viral cathepsin Protein (His & Myc)

Cat.No: TMPH-00060

Species: ApNPV

Expression System: E. coli

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